One day on the set of Alfred Hitchcock's Lifeboat (1944), Mary Anderson, eager to perform to the best of her ability, asked the director which side he considered to be her best. Hitchcock replied without looking up: "My dear," he declared, "you're sitting on it."
[Hitchcock, who made a cameo in many of his films, appeared in Lifeboat -- in a weight-loss ad in a newspaper.]