As the car passed the Texas Schoolbook Depository, Kennedy was addressed by Governor Connelly's wife: "Mr. President, you can't say that Dallas doesn't love you," she declared, prompting Kennedy's last (tragically ironic) words before he was shot: "That's obvious."
(In fact, Kennedy had been greeted that morning by handbills calling him a traitor.)
Oswald's last words were more ironic still. "There ain't nobody," he declared as he was being transfered to a county jail, "gonna shoot me." Moments later Oswald was shot by Jack Ruby.
[If Oswald was indeed a Communist patsy, the final film which JFK saw before his ill-fated trip was also rather ironic: From Russia With Love.]