[In 1535, French explorer Jacques Cartier observed Iroquoi indians chewing tobacco along the St. Lawrence River. "When we tried to use it," Cartier wrote, "we found it bit our tongues like pepper." Explorers soon brought the plant back to Europe, where it was billed as a panacea for everything from gonorrhea to flatulence. It was even promoted as a dentifrice -- to whiten teeth!]