During the filming of In the Line of Fire, John Malkovich often entertained Rene Russo in the makeup trailer, cracking her up with a creaky Midwestern imitation of his mother. One day, Russo had to leave the trailer. Why? Explained Russo: "I was peeing in my pants!"
[Fun fact: In a bid to address California's water shortage at the turn of the millennium, Russo lead a campaign to promote hardy native shrubs in place of lawns.]